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Unique pathways downstream of TLR-4 and TLR-7 activation: sex-dependent behavioural, cytokine, and metabolic consequences.

Isobel K DunstanRoss McLeodDaniel E Radford-SmithWenzheng XiongTrinity PateFay ProbertDaniel C Anthony
Published in: Frontiers in cellular neuroscience (2024)
The results highlight how the cytokine profile induced by one PAMP cannot be extrapolated to another, but they do reveal how the manipulation of the conserved metabolome response might afford a more generic approach to the treatment of post-infection syndromes.
Keyphrases
  • toll like receptor
  • inflammatory response
  • immune response
  • transcription factor
  • nuclear factor
  • genome wide
  • gene expression
  • dna methylation
  • combination therapy
  • replacement therapy