Automated Evaluation of Ellipsoid Zone At-Risk Burden for Detection of Hydroxychloroquine Retinopathy.

Katherine E TalcottPatrick W Commiskey Hasan CetinYavuz CakirJon WhitneyJordan BudrevichJamie L ReeseSunil K SrivastavaJustis P Ehlers

Published in: Journal of personalized medicine (2024)

The novel biomarker EZ-At Risk was significantly higher in subjects with evidence of HCQ retinopathy as well as significantly associated with HCQ dose. This novel biomarker should be further evaluated as a potential screening tool for subjects on HCQ.

Keyphrases

machine learning
deep learning
high throughput
loop mediated isothermal amplification
risk factors
human health
risk assessment