Slowing processing speed is associated with cognitive fatigue in newly diagnosed multiple sclerosis patients.

Marco PitteriCaterina DaporJohn DeLucaNancy D ChiaravallotiDamiano MarastoniMassimiliano Calabrese

Published in: Journal of the International Neuropsychological Society : JINS (2022)

CF can be detected even in newly diagnosed pwMS and might objectively manifest as a progressive increase in omissions during a sustained highly demanding task (i.e., PASAT). This pattern may reflect slowed processing speed and increased fatigue in pwMS. Focusing on omissions on the PASAT instead of correct responses only may improve its specificity as an objective measure of CF.

Keyphrases

newly diagnosed
multiple sclerosis
cystic fibrosis
end stage renal disease
sleep quality
physical activity
chronic kidney disease
depressive symptoms
patient reported