Relationships between the Nicotine Metabolite Ratio and a Panel of Exposure and Effect Biomarkers: Findings from Two Studies of U.S. Commercial Cigarette Smokers.
Dana M CarrollSharon E MurphyNeal L BenowitzAndrew A StrasserMichael KotlyarStephen S HechtSteven G CarmellaFrancis J McClernonLauren R PacekSarah S DermodyRyan G VandreyEric C DonnyDorothy K HatsukamiPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2020)
This is the first documentation that NMR is not only associated with smoking exposure but also biomarkers of biological effects that are integral in the development of tobacco-related disease. Results provide support for NMR as a biomarker for understanding a smoker's exposure and potential risk for tobacco-related disease.