Mutant RAS-driven Secretome Causes Skeletal Muscle Defects in Breast Cancer.
Ruizhong WangAditi S KhatpeBrijesh KumarHenry Elmer MangKatie BaticAdedeji K AdebayoHarikrishna NakshatriPublished in: Cancer research communications (2024)
Mutant RAS- and PIK3CA-driven breast cancers distinctly affect the function of skeletal muscle. Therefore, research and therapeutic targeting of cancer-induced systemic effects need to take aberrant cancer genome into consideration.