Mixture model analysis identifies irritable bowel syndrome subgroups characterised by specific profiles of gastrointestinal, extraintestinal somatic and psychological symptoms.

Annikka V PolsterL Van OudenhoveM JonesL ÖhmanH TörnblomM Simrén

Published in: Alimentary pharmacology & therapeutics (2017)

This model-based subgrouping of IBS partly supports the distinction of subgroups based on bowel habits, but additionally distinguishes subgroups with or without co-morbid extraintestinal somatic and psychological symptoms. The resulting groups show specific profiles of symptom combinations.

Keyphrases

irritable bowel syndrome
sleep quality
copy number
bariatric surgery
genome wide
dna methylation
gene expression
obese patients
patient reported