Comet-FISH analysis of urothelial cells. A screening opportunity for bladder cancer?

From a prevention perspective, the alkaline Comet-FISH could be a valuable tool with broad potential for clinical application. Furthermore, comet assay could be more beneficial for diagnosing and monitoring bladder cancer and determining individual susceptibility. Thus, we recommend further studies to understand the potential of this combined assay in the general population as a potential screening test and in patients initiated into the diagnostic process.