Congenital malformations and preeclampsia associated with integrase inhibitor use in pregnancy: A single-center analysis.
Christiana SmithAngela J FoughtJoyce F SungJennifer R McKinneyTorri D MetzKirk B FettersSarah LazarusShannon CapraroEmily BarrCarrie GlennyJenna BuehlerAdriana Weinbergnull nullPublished in: PloS one (2023)
In our cohort, first-trimester INSTI exposure was associated with increased rates of congenital anomalies and use of INSTI during pregnancy was associated with preeclampsia. These findings underscore the need for continued monitoring of the safety of INSTI in pregnancy.