Obese patients with long COVID-19 display abnormal hyperventilatory response and impaired gas exchange at peak exercise.
Mickael Rejaudry LacavalerieSandrine Pierre-FrancoisMoustapha AgossouJocelyn InamoAndré CabieJosé Luis BarnayRemi NevierePublished in: Future cardiology (2022)
Aim: To analyze the impact of obesity on cardiopulmonary response to exercise in people with chronic post-COVID-19 syndrome. Patients & methods: Consecutive subjects with chronic post-COVID syndrome 6 months after nonsevere acute infection were included. All patients received a complete clinical evaluation, lung function tests and cardiopulmonary exercise testing. A total of 51 consecutive patients diagnosed with chronic post-COVID-19 were enrolled in this study. Results: More than half of patients with chronic post-COVID-19 had a significant alteration in aerobic exercise capacity (VO 2 peak) 6 months after hospital discharge. Obese long-COVID-19 patients also displayed a marked reduction of oxygen pulse (O 2 pulse). Conclusion: Obese patients were more prone to have pathological pulmonary limitation and pulmonary gas exchange impairment to exercise compared with nonobese COVID-19 patients.
Keyphrases
- sars cov
- coronavirus disease
- obese patients
- end stage renal disease
- bariatric surgery
- ejection fraction
- lung function
- newly diagnosed
- high intensity
- type diabetes
- metabolic syndrome
- weight loss
- prognostic factors
- blood pressure
- pulmonary hypertension
- intensive care unit
- resistance training
- case report
- adipose tissue
- roux en y gastric bypass
- chronic obstructive pulmonary disease
- patient reported outcomes
- insulin resistance
- clinical evaluation
- room temperature
- respiratory failure
- body composition
- mechanical ventilation
- skeletal muscle
- carbon dioxide
- patient reported