Genome tumor profiling in endometrial cancer and clinical relevance in endometrial cancer management: a retrospective single-center experience.
Vanda SalutariViola GhizzoniMaria Vittoria CarboneElena GiudiceSerena CappuccioFrancesco FanfaniGiovanni ScambiaDomenica LorussoPublished in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2023)
This study highlights the importance of characterizing the mutation profile of patient tumors through NGS. Our findings suggest a clinical benefit of using NGS-driven targeted therapies in endometrial carcinoma patients. However, this personalized approach could benefit the health system in terms of cost-effectiveness by reducing the costs of inappropriate, ineffective, and often expensive treatments.