Jiedu Yizhi Formula Improves Cognitive Function by Regulating the Gut Dysbiosis and TLR4/NF-κB Signaling Pathway.

Pengqi ZhangTianye WangXiaoting ZhuLina FengJiale WangYunqiang LiXinyue ZhangTingting CuiMingquan Li

Published in: Neuropsychiatric disease and treatment (2023)

The findings revealed that JDYZF improved cognitive ability and alleviated the TLR4/NF-κB signaling pathway in APP/PS1 mice, and the modulating the gut microbiota presented here may help illuminate its activation mechanism.

Keyphrases

signaling pathway
pi k akt
toll like receptor
inflammatory response
induced apoptosis
immune response
epithelial mesenchymal transition
nuclear factor
lps induced
high fat diet induced
type diabetes
metabolic syndrome
oxidative stress
wild type
low birth weight