Neurodevelopmental outcomes at 2 years in children who received sildenafil therapy in utero: The STRIDER randomised controlled trial.

Andrew N SharpChristine CornforthRichard JacksonJane HarroldMark A TurnerLouise C KennyPhilip N BakerEdward D JohnstoneAsma Khalil Peter Von DadelszenAris T PapageorghiouZarko AlfirevicBrigitte Vollmernull null

Published in: BJOG : an international journal of obstetrics and gynaecology (2024)

Sildenafil therapy did not prolong pregnancy or improve perinatal outcomes and did not improve infant neurodevelopment in FGR survivors. Therefore, sildenafil should not be prescribed for this condition.

Keyphrases

pulmonary hypertension
pulmonary arterial hypertension
young adults
study protocol
type diabetes
clinical trial
adipose tissue
cell therapy
glycemic control
smoking cessation
replacement therapy