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Evaluation of nefrotoxicity by tacrolimus and micophenolate mofetil associated with kidney ischemia and reperfusion: experimental study in rats.

Alexandre Cavalheiro CavalliLuis Fernando Macente SalaJulio SlongoRogério de FragaRenato Tambara Filho
Published in: Revista do Colegio Brasileiro de Cirurgioes (2022)
Both drugs cause changes in renal function. Glomerular morphometry and stereology showed negative interference of immunosuppressants during compensatory glomerular hypertrophy.
Keyphrases
  • diabetic nephropathy
  • high glucose
  • acute myocardial infarction
  • cerebral ischemia
  • acute ischemic stroke
  • endothelial cells
  • drug induced
  • brain injury
  • blood brain barrier
  • subarachnoid hemorrhage