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Iron increases the profibrotic properties of the senescent peritoneal mesothelial cells.

Bręborowicz Andrzej
Published in: The International journal of artificial organs (2023)
MC aging results in change of their genotype and phenotype which lead to their profibrotic effect. Exposure to iron enhances these changes.
Keyphrases
  • induced apoptosis
  • iron deficiency
  • cell cycle arrest
  • endoplasmic reticulum stress
  • signaling pathway
  • high glucose
  • endothelial cells