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Tumid Lupus Erythematosus (TLE): A Review of a Rare Variant of Chronic Cutaneous Lupus Erythematosus (cCLE) with Emphasis on Differential Diagnosis.

Maged DaruishFrancesca AmbrogioCaterina FotiAlessandra FilosaGerardo Cazzato
Published in: Diagnostics (Basel, Switzerland) (2024)
Tumid lupus erythematosus (TLE) has been the subject of heated debate regarding its correct nosographic classification. The definition of TLE has changed over time, varying according to the different studies performed. In this review, we address the initial definition of TLE, the changes that have taken place in the understanding of TLE, and its placement within the classification of cutaneous lupus erythematosus (CLE), with a focus on clinical, histopathological, immunophenotypical, and differential diagnosis aspects.
Keyphrases
  • systemic lupus erythematosus
  • disease activity
  • machine learning
  • deep learning
  • rheumatoid arthritis
  • ultrasound guided
  • drug induced