Highly selective γ-alkoxylation, γ-amination and γ-alkylation of unbiased enals by means of photoredox catalysis.

We report herein a general and highly selective γ-functionalization protocol under visible light irradiation. This mild radical approach enables the expansion of the scope of application to unbiased enals and the introduction of a wide variety of alkoxy, amino and alkyl functionalities in the γ position with complete regioselectivity.