BCP crystals promote chondrocyte hypertrophic differentiation in OA cartilage by sequestering Wnt3a.

Jessica BertrandTabea KräftTobias GronauJoanna SherwoodFrank RutschFrédéric LiotéFrancesco Dell'AccioChristoph H LohmannMiriam BollmannAnnelena HeldThomas Pap

Published in: Annals of the rheumatic diseases (2020)

Consequently, our data identify BCP crystals as a concentrating factor for Wnt3a in the pericellular matrix and an inducer of chondrocyte hypertrophy.

Keyphrases

cell proliferation
stem cells
room temperature
electronic health record
knee osteoarthritis
deep learning