Urokinase-plasminogen activator protects periodontal ligament fibroblast from oxidative induced-apoptosis and DNA damage.

M S Ahmad AkhoundiA RoknR BagheriN MomeniMahshid Hodjat

Published in: Journal of periodontal research (2018)

The present study brings support to the theory that uPA may have a protective role for periodontal tissue and could protect PDL fibroblasts from oxidative DNA damage and apoptosis.

Keyphrases

dna damage
oxidative stress
induced apoptosis
endoplasmic reticulum stress
dna repair
signaling pathway
cell cycle arrest
cell proliferation
wound healing