Sleep functional connectivity, hyperexcitability, and cognition in Alzheimer's disease.

Sebastian G MoguilnerCourtney BerezukAlex C BenderKyle R PellerinStephen N GompertsSydney S CashRani A SarkisAlice D Lam

Published in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)

Brain functional connectivity (FC) in Alzheimer's disease is altered during sleep. Sleep FC measures correlate with cognitive decline in AD. Network hyperexcitability in AD has a distinct sleep connectivity signature.

Keyphrases

functional connectivity
resting state
cognitive decline
mild cognitive impairment
sleep quality
physical activity
blood brain barrier