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Ovarian mesonephric-like adenocarcinoma arising in serous borderline tumor: a case report with complex morphological and molecular analysis.

Pavel DundrMária GregováKristýna NěmejcováMichaela BártůNikola HájkováJan HojnýIvana StružinskáDaniela Fischerová
Published in: Diagnostic pathology (2020)
Our result support the theory that at least some mesonephric-like ovarian adenocarcinomas are of Müllerian origin. The serous borderline tumor seems to be a precursor of mesonephric-like adenocarcinoma, which has been proven in our case by both tumors sharing the same mutations, and the presence of cumulative molecular aberrations in the mesonephric-like adenocarcinoma.
Keyphrases
  • high grade
  • squamous cell carcinoma
  • locally advanced
  • social media
  • copy number
  • gene expression
  • health information
  • dna methylation
  • squamous cell