A retrospective analysis of 122 immune thrombocytopenia patients treated with dapsone: Efficacy, safety and factors associated with treatment response.
Marina Pereira ColellaFernanda A OrsiElizio C F AlvesGabriela de F DelmoroGabriela G Yamaguti-HayakawaErich Vinicius De PaulaJoyce M Annichino-BizzacchiPublished in: Journal of thrombosis and haemostasis : JTH (2021)
Our findings suggest that dapsone has adequate efficacy and is well tolerated. Although the mechanism of action is still unclear, our observation that the degree in the drop of hemoglobin is greater in responders suggest a possible role of the blockage of the reticuloendothelial system in the therapeutic effect of the drug.