Sustained remission after haploidentical bone marrow transplantation in a child with refractory systemic juvenile idiopathic arthritis.
Guillaume MorelleMartin CastelleGraziella PintoSylvain BretonMatthieu BendavidCharlotte BoussardRichard MouyBrigitte Bader-MeunierMichaela SemeraroAlbert FayeMarina CavazzanaBénédicte NevenStéphane BlanchePierre Quartier Dit MaireDespina MoshousPublished in: Pediatric rheumatology online journal (2021)
Allogenic HSCT may be a therapeutic option, even with a HLA haplo-identical alternative donor, in patients with inflammatory diseases such as SJIA. Despite increased experience with this treatment, the risk of life-threatening complications restrains its indication to selected patients with severe, refractory disease.