Acute haematogenous periprosthetic joint infection due to Streptococcus sanguinis along with coexistent crystalline arthropathy after total knee arthroplasty: a rare combination.
Joost B MalkusLouren M GoedhartWiebe C VerraPublished in: BMJ case reports (2022)
A man in his 60s, with a medical history of gout, underwent total knee arthroplasty of his right knee followed by expeditious rehabilitation. Seven months after surgery, he was referred to the emergency ward with sudden onset of pain and swelling of his right knee accompanied with fever. Further inquiry revealed no trauma, infection or skin lesions besides a tongue bite several weeks earlier. An impaired range motion of the knee was seen on physical examination along with a tachycardia. Laboratory studies showed a C reactive protein of 345 mg/L, after which a debridement, antibiotics and implant retention procedure was performed. Intraoperatively obtained synovial fluid showed monosodium urate crystals consistent with crystalline arthropathy (ie, gout). However, unexpectedly, Streptococcus sanguinis was identified in all microbiological cultures too, confirming a coexistent periprosthetic joint infection. After comprehensive antibiotic treatment and gout flare therapy, this patient made a full recovery with retention of the implant.
Keyphrases
- total knee arthroplasty
- total hip
- uric acid
- soft tissue
- room temperature
- healthcare
- pain management
- biofilm formation
- candida albicans
- public health
- emergency department
- liver failure
- chronic pain
- physical activity
- case report
- knee osteoarthritis
- metabolic syndrome
- escherichia coli
- single cell
- neuropathic pain
- drug induced
- total hip arthroplasty
- replacement therapy
- anterior cruciate ligament
- anterior cruciate ligament reconstruction
- aortic dissection
- minimally invasive
- stem cells
- intensive care unit
- cystic fibrosis
- mesenchymal stem cells
- catheter ablation
- wound healing
- spinal cord
- trauma patients
- cell therapy
- preterm birth
- extracorporeal membrane oxygenation
- atrial fibrillation