Hippocampal subfield atrophy of CA1 and subicular structures predict progression to dementia in idiopathic Parkinson's disease.

Audrey LowHeidi FooTing Ting YongLouis C S TanNagaendran Kandiah

Published in: Journal of neurology, neurosurgery, and psychiatry (2019)

Early atrophy of CA1, subiculum and presubiculum preceded, and predicted, PDD conversion. Differential patterns of subfield atrophy were also observed among those who progressed to PDD and were associated with impaired executive functions.

Keyphrases

mild cognitive impairment
high resolution
cognitive impairment
brain injury
cerebral ischemia
mass spectrometry