Comparison of the Seventh and Eighth Edition of American Joint Committee on Cancer (AJCC) Staging for Selected and Nonselected Oropharyngeal Squamous Cell Carcinomas.
Pooja VijayvargiyaSumita TrivediManali RupjiHaocan SongYuan LiuRenjian JiangAzeem S KakaGeorgia Z ChenWilliam StokesConor SteuerDong M ShinJonathan J BeitlerMihir R PatelAshley AikenNabil F SabaPublished in: The oncologist (2022)
The overall performance of discrimination improved from AJCC 7 to AJCC 8 for both clinically selected and unselected patients, but more notably for our HPV-selected cohort. Despite the lack of statistically significant differentiation between Stages I and II in AJCC 8 in either groups, markedly improved discrimination was observed between Stages I/II, III, and IV in the HPV-selected cohort.