Pharmacokinetic and Tissue Distribution of Orally Administered Cyclosporine A-Loaded poly(ethylene oxide)-block-Poly(ε-caprolactone) Micelles versus Sandimmune® in Rats.
Ziyad BinkhathlanRaisuddin AliWajhul QamarHanan Al-LawatiAfsaneh LavasanifarPublished in: Pharmaceutical research (2021)
The results point to the influence of excipients in Sandimmune® on CyA disposition and more inert nature of PEO-b-PCL micelles in defining CyA biological interactions.