Interstitial lung disease in patients with connective tissue disease: Subtypes, clinical features and comorbidities in the Western Cape, South Africa.
E PalalaneDeshiré Alpizar-RodriguezS BothaMariam Q Said-HartleyGregory L CalligaroBridget HodkinsonPublished in: African journal of thoracic and critical care medicine (2022)
Clinical features, chest X-rays and pulmonary function tests correlated poorly with high-resolution computerised tomography (HRCT).Smoking, environmental toxins, gastro-oesophogeal reflux and previous pulmonary tuberculosis infection were significant comorbidities in CTD-ILD patients.Early screening of ILD with HRCT is recommended, particularly in SSc.Use of MTX before and after ILD diagnosis was not associated with acute pneumonitis.
Keyphrases
- interstitial lung disease
- south africa
- systemic sclerosis
- pulmonary tuberculosis
- rheumatoid arthritis
- idiopathic pulmonary fibrosis
- high resolution
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- mycobacterium tuberculosis
- ejection fraction
- peritoneal dialysis
- liver failure
- risk assessment
- respiratory failure
- intensive care unit
- clinical decision support
- hepatitis b virus
- hepatitis c virus