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Bioactivity-based molecular networking-guided identification of guttiferone J from Garcinia cambogia as an anti-obesity candidate.

Zheling FengJiali ChenCheng ChenLu FengRui WangJianzhong ZhuRuohan LouJia LiuYang YeLi-Gen Lin
Published in: British journal of pharmacology (2022)
GOJ represents a new scaffold of thermogenic inducer, which is responsible for the anti-obesity property of G. cambogia and can be further developed as a candidate for treating obesity and its related disorders.
Keyphrases
  • insulin resistance
  • metabolic syndrome
  • weight loss
  • high fat diet induced
  • type diabetes
  • weight gain
  • adipose tissue
  • body mass index
  • physical activity