A comprehensive study of alternative splicing in malignant pleural mesothelioma identifies potential therapeutic targets in a new cluster with poor survival.

Ming-Ming ShaoXin QiaoQing-Yu ChenFeng-Shuang Yi

Published in: Thoracic cancer (2022)

We performed unsupervised clustering of alternative splicing data from 84 MPM patients from the TCGA database and identified a cluster associated with the worst prognosis that was sensitive to a GSK-3 inhibitor.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
machine learning
signaling pathway
electronic health record
genome wide
dna methylation
rna seq
artificial intelligence
drug induced