Therapeutic role of mesenchymal stem cell-derived extracellular vesicles in neuroinflammation and cognitive dysfunctions induced by binge-like ethanol treatment in adolescent mice.

Susana MelladoCarlos M CuestaSandra MontagudMarta Rodríguez-AriasVictoria Moreno-ManzanoConsuelo GuerriConsuelo Guerri

Published in: CNS neuroscience & therapeutics (2023)

Taken together, these results provide the first evidence for the therapeutic potential of the MSC-derived EVs in the neuroimmune response and cognitive dysfunction induced by binge alcohol drinking in adolescence.

Keyphrases

mesenchymal stem cells
alcohol consumption
depressive symptoms
mental health
traumatic brain injury
bone marrow
high fat diet induced
stem cells
umbilical cord
insulin resistance
replacement therapy
blood brain barrier