Highly clarithromycin-resistant Helicobacter pylori infection in asymptomatic children from a rural community of Cajamarca-Peru.
Miguel Angel Aguilar-LuisFernando Palacios-CuervoFátima Espinal-ReyesAndrea Calderón-RiveraSaúl Levy-BlitchteinCarlos Palomares-ReyesWilmer Silva-CasoVictor Zavaleta-GavidiaJorge Bazán-MayraAngela Cornejo-TapiaJuana Mercedes Del Valle-MendozaLuis J Del VallePublished in: BMC research notes (2018)
Helicobacter pylori was detected in 17.2% (49/285) of the samples. Unboiled water consumption the most frequent associated factor in patients with positive PCR for H. pylori infection (93.9%). Clarithromycin resistant mutations were found in 79.6% (39/49) of the positive samples for H. pylori. The most frequent mutation was A2142G (46.9%), followed by the double-mutation A2142G-A2143G (28.6%).