Specific metabolic syndrome components predict cognition and social functioning in people with type 2 diabetes mellitus and severe mental disorders.
Joan Vicent Sánchez-OrtíVicent Balanzá-MartínezPatricia Correa-GhisaysGabriel Selva-VeraJoan Vila-FrancésRafael Magdalena-BeneditoConstanza San-MartinVíctor M VictorIrene Escribano-LopezAntonio Hernández-MijaresJuliana Vivas-LalindeJacqueline Mayoral-van SonRafael Tabarés-SeisdedosPublished in: Acta psychiatrica Scandinavica (2022)
Specific MetS components are significantly associated with cognitive impairment across somatic and psychiatric disorders. Our findings provide further evidence on the summative effect of MetS components to predict cognition and social functioning and allow the identification of individuals with worse outcomes. Transdiagnostic, lifestyle-based therapeutic interventions targeted at that group hold the potential to improve health outcomes.
Keyphrases
- metabolic syndrome
- cognitive impairment
- healthcare
- mental health
- physical activity
- mild cognitive impairment
- white matter
- cardiovascular disease
- early onset
- insulin resistance
- uric acid
- weight loss
- cancer therapy
- multiple sclerosis
- cardiovascular risk factors
- drug delivery
- gene expression
- risk assessment
- genome wide
- glycemic control