The yield of full BRCA1/2 genotyping in Israeli Arab high-risk breast/ovarian cancer patients.

Rinat Bernstein-MolhoInbal Barnes-KedarMark D LudmanGili ReznikHagit Baris FeldmanNadra Nasser SamraAvital EilatTamar PeretzLilach Peled PeretzTamar ShapiraNurit MagalMarina Lifshitc KalisRinat YerushalmiChana VinklerSari LibermanLina Basel-SalmonMordechai ShohatEphrat Levy-LahadEitan FriedmanLily BazakYael Goldberg

Published in: Breast cancer research and treatment (2019)

The overall yield of comprehensive BRCA1/2 testing in high-risk Israeli Arab individuals is low in breast cancer patients, and much higher in ovarian cancer patients. These results may guide optimal cancer susceptibility testing strategy in the Arab-Israeli population.

Keyphrases

papillary thyroid
high throughput
genome wide
squamous cell
breast cancer risk
squamous cell carcinoma
genetic diversity
young adults