Histopathological, immunohistochemical, and biomechanical effects of splenectomy on Achilles tendon healing in rats.

Serdar YükselM Akif GuleçZeki GultekinAysel CaglarOzan BeytemurEnder AlagozA Akdogan EkerCansu SubaşıErdal Karaoz

Published in: Connective tissue research (2018)

Splenectomy may positively influence Achilles tendon healing through modification of the proinflammatory/anti-inflammatory ratio in favor of anti-inflammatory cytokines by causing a decrease in spleen-originated inflammatory cells.

Keyphrases

anti inflammatory
induced apoptosis
cell cycle arrest
oxidative stress
cell death
endoplasmic reticulum stress
signaling pathway
cell proliferation