Take Control: A randomized trial evaluating the efficacy and safety of self- versus physician-managed titration of insulin glargine 300 U/mL in patients with uncontrolled type 2 diabetes.

David L Russell-JonesArnaud DauchyElías DelgadoGeorge DimitriadisHans A FrandsenLuiza PopescuBernd SchultesKrzysztof StrojekMireille BonnemaireAude Roborel de ClimensMelanie Jane Davies

Published in: Diabetes, obesity & metabolism (2019)

Self-managed titration of Gla-300 was superior to physician-managed titration in terms of HbA1c reduction, accompanied by similar total PRO scores, with a clinically relevant reduction in emotional burden, and similar hypoglycaemia frequency.

Keyphrases

type diabetes
glycemic control
primary care
emergency department
cardiovascular disease
insulin resistance
risk factors
adipose tissue