Lithium is able to minimize olanzapine oxidative-inflammatory induction on macrophage cells.

Marcelo Soares FernandesFernanda BarbisanVerônica Farina AzzolinPedro Antônio Schmidt do Prado-LimaCibele Ferreira TeixeiraIvo Emílio da Cruz JungCharles Elias AssmannRogerio Tomasi RiffelMarta Maria Medeiros Frescura DuarteEdnea Maia Aguiar-RibeiroIvana Beatrice Mânica da Cruz

Published in: PloS one (2019)

Despite methodological limitations related to in vitro protocols, results suggested that Li may attenuate OLZ-induced oxidative and inflammatory responses that result from metabolic side effects associated with OLZ.

Keyphrases

induced apoptosis
cell cycle arrest
oxidative stress
high glucose
solid state
drug induced
adipose tissue
endoplasmic reticulum stress
signaling pathway
cell death
cell proliferation