Randomized Laboratory Study of Single-Dose Cannabis, Dronabinol, and Placebo in Patients With Schizophrenia and Cannabis Use Disorder.

Mary F BrunetteRobert M RothChristi TraskJibran Y KhokharJames C FordSoo Hwan ParkSara M HickeyThomas ZeffiroHaiyi Xie

Published in: Schizophrenia bulletin (2024)

In people with SCZ-CUD, a modest single dose of oral THC was associated with worse cognitive functioning without symptom exacerbation several hours after administration, and a THC dose-response effect was seen for negative symptoms.

Keyphrases

double blind
phase iii
placebo controlled
chronic obstructive pulmonary disease
open label
clinical trial
intensive care unit