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Beyond type 2 asthma biomarkers: risk stratification for NSAID-exacerbated respiratory disease.

Jacqueline Pérez-PazosAsunción García-SánchezMiguel EstravísEmma Moreno-JimenezNatalia MorgadoManuel Gómez-GarcíaJacinto Ramos-GonzálezMaría Gil-MelcónCristina Martín-GarcíaFrancisco Javier Muñoz-BellidoCatalina SanzMaría Isidoro-GarcíaIgnacio Dávila González
Published in: ERJ open research (2024)
We validated the transcriptomic data of five differentially expressed genes in T2 asthma. Different patterns of association were identified in patient stratification, suggesting that different molecular mechanisms underlie the spectrum of T2 asthma. Potential biomarkers were also found and used to design an algorithm with practical diagnostic utility for T2 asthma, including risk stratification for N-ERD.
Keyphrases
  • chronic obstructive pulmonary disease
  • lung function
  • allergic rhinitis
  • cystic fibrosis
  • air pollution
  • single cell
  • electronic health record