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A 3-day course of 1 mg/kg versus 2 mg/kg bodyweight prednisolone for 1- to 5-year-old children with acute moderate exacerbation of asthma: a randomized double-blind noninferiority trial.

Pavan Kumar BuddalaChandrasekaran VenkateshK T Harichandrakumar
Published in: Paediatrics & child health (2020)
Prednisolone at a dose of 1 mg/kg/day was not inferior to 2 mg/kg/day in terms of clinical improvement and recurrence of wheeze within 1 week and has less frequent vomiting compared to higher dose.
Keyphrases
  • chronic obstructive pulmonary disease
  • clinical trial
  • double blind
  • phase iii
  • study protocol
  • placebo controlled
  • lung function
  • air pollution
  • extracorporeal membrane oxygenation