Integrating Genome and Methylome Data to Identify Candidate DNA Methylation Biomarkers for Pancreatic Cancer Risk.

Jingjing ZhuYaohua Yang John B KisielDouglas W MahoneyDominique S MichaudXingyi GuoWilliam R TaylorXiao-Ou ShuXiang ShuDuo LiuBingshan LiRan TaoQiuyin Cai Quan LongJirong LongLang Wu

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2021)

A comprehensive study using genetic instruments identifies 45 CpG sites at nine genomic loci for pancreatic cancer risk.

Keyphrases

genome wide
dna methylation
copy number
gene expression
electronic health record
big data
patient reported outcomes
deep learning
genome wide association