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Evaluation of syringin's neuroprotective effect in a model of neonatal hypoxic-ischemic brain injury.

Ezgi Yangın ErgonAslı CelikAyşe Gülden DinizRuya ÇolakSenem Alkan ÖzdemirSebnem CalkavurOsman Yılmaz
Published in: Turkish journal of medical sciences (2023)
SYR reduced apoptosis, perivascular and pericellular edema, and neuronal degeneration in rat cerebral tissue. These results raise the possibility that SYR may have a neuroprotective effect on the harm brought on by HIE. This is the first investigation of SYR's function within the HIE paradigm.
Keyphrases
  • brain injury
  • cerebral ischemia
  • subarachnoid hemorrhage
  • oxidative stress
  • blood brain barrier
  • cell death
  • endoplasmic reticulum stress
  • cell cycle arrest
  • signaling pathway