Construction of Spironaphthalenones via Gold-Catalyzed Intramolecular Dearomatization Reaction of β-Naphthol Derivatives.

Lu DingWen-Ting WuLiming Zhang Shu-Li You

Published in: Organic letters (2020)

A gold-catalyzed dearomatization reaction of β-naphthol derivatives via intramolecular hydroalkylation of alkynes is described. In the presence of 5 mol % Au complex, various spironaphthalenones were obtained from α-tethered alkyne β-naphthols in good to excellent yields (76-99%) under open-flask conditions.

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