Trans-Synaptic Degeneration Following Acute Optic Neuritis in Multiple Sclerosis.

Olwen C Murphy Elias S SotirchosGrigorios KalaitzidisEleni S VasileiouHenrik EhrhardtJeffrey LambeOhemaa KwakyiJames NguyenAlexandra Zambriczki LeeJulia ButtonBlake E DeweyScott D NewsomeEllen M MowryKathryn C FitzgeraldJerry L PrincePeter A CalabresiShiv Saidha

Published in: Annals of neurology (2022)

These results provide in-vivo evidence for anterograde trans-synaptic degeneration following AON in PwMS, and suggest that trans-synaptic degeneration may be related to clinically-relevant visual outcomes. ANN NEUROL 2022.

Keyphrases

multiple sclerosis
prefrontal cortex
liver failure
drug induced
optical coherence tomography
respiratory failure
type diabetes
adipose tissue
metabolic syndrome
intensive care unit
hepatitis b virus
neural network