Reduced sensitivity of PLASMIC and French scores for the diagnosis of thrombotic thrombocytopenic purpura in older individuals.
Angela LiuNoor DhaliwalHarshvardhan UpretiJamil KasmaniKathryn DaneAlison MoliternoEvan BraunsteinRobert BrodskyShruti ChaturvediPublished in: Transfusion (2020)
The PLASMIC and French TTP scores have reduced sensitivity at age ≥ 60 years and are less reliable in identifying TTP in older patients. A high index of suspicion and availability of rapid ADAMTS13 assays is required to correctly diagnose all patients with TTP.