High-performing fiber electrodes based on a gold-shelled silver nanowire framework for bioelectronics.

Flexible fiber electrodes offer new opportunities for bioelectronics and are reliable in vivo applications, high flexibility, high electrical conductivity, and satisfactory biocompatibility are typically required. Herein, we present an all-metal flexible and biocompatible fiber electrode based on a metal nanowire hybrid strategy, i.e. , silver nanowires were assembled on a freestanding framework, and further to render them inert, they were plated with a gold nanoshell. Our fiber electrodes exhibited a low modulus of ∼75 MPa and electrical conductivity up to ∼4.8 × 10 6 S m -1 . They can resist chemical erosion with negligible leakage of biotoxic silver ions in the physiological environment, thus ensuring satisfactory biocompatibility. Finally, we demonstrated the hybrid fiber as a neural electrode that stimulated the sciatic nerve of a mouse, proving its potential for applications in bioelectronics.