The ability of a 3-gene host signature in blood to distinguish tuberculous meningitis from other brain infections.

Julie HuynhNhat Hoang Thanh LeBao Hoai Le NguyenHai Thanh HoangThu Anh Dang DoTram Thi Bich TrinhDung Thi Mong VuVinh Dinh DoNgoc My NgiemJoseph DonovanPhu Hoan NguyenThanh Van DangThu Thi Anh NguyenBang Duc NguyenHa Minh Thi DangNghia Trung Dang HoTan Van LeVan Hong LeGuy ThwaitesNguyen Thuy Thuong Thuong

Published in: The Journal of infectious diseases (2024)

The 3-gene host signature in whole blood has the ability to discriminate TBM from other brain infections, including in HIV-positive individuals. Validation in large prospective diagnostic study is now required.

Keyphrases

hiv positive
men who have sex with men
resting state
antiretroviral therapy
white matter
south africa
copy number
genome wide
genome wide identification
functional connectivity
human immunodeficiency virus
gene expression
hiv infected
multiple sclerosis
hepatitis c virus
blood brain barrier