Treatment patterns, healthcare resource utilization and outcomes for early stage triple-negative breast cancer in Japan.
Hitomi SannoKazuko TaniguchiYuya YoshimotoShigehira SajiPublished in: Future oncology (London, England) (2024)
Aim: There is limited information regarding the treatment and outcomes of early stage triple-negative breast cancer (esTNBC) in real-world settings in Japan. Materials & methods: Retrospective analyses of the Medical Data Vision database assessed treatment patterns, healthcare resource utilization (HCRU), patient characteristics, outcomes and prognostic factors among four groups (neoadjuvant therapy+surgery+adjuvant therapy; neoadjuvant therapy+surgery; surgery+adjuvant therapy; surgery only) of esTNBC patients. Results: Treatment patterns, HCRU and demographics varied among the four groups. HCRU was greater and prognosis tended to be worse in the neoadjuvant+surgery+adjuvant therapy group. Conclusion: Our results provide insights into the treatment practices, HCRU and prognosis of esTNBC in Japan. The treatment practices were heterogeneous, reflecting the decision-making process in Japan during the study period.
Keyphrases
- healthcare
- early stage
- minimally invasive
- prognostic factors
- primary care
- combination therapy
- rectal cancer
- machine learning
- type diabetes
- metabolic syndrome
- ejection fraction
- insulin resistance
- chronic kidney disease
- locally advanced
- bone marrow
- social media
- electronic health record
- percutaneous coronary intervention
- smoking cessation
- health information