Tissue alkaline phosphatase activity and expression in an experimental infant swine model of cardiopulmonary bypass with deep hypothermic circulatory arrest.
Ludmila KhailovaJustin RobisonJames JaggersRichard IngScott LawsonAmy TreeceDanielle SorannoSuzanne Osorio LujanJesse A DavidsonPublished in: Journal of inflammation (London, England) (2020)
Changes in alkaline phosphatase activity after cardiopulmonary bypass with deep hypothermic circulatory arrest and bovine intestinal alkaline phosphatase delivery are tissue specific. Kidneys, lung, and ileal alkaline phosphatase appear most affected by cardiopulmonary bypass with deep hypothermic circulatory arrest and further research is warranted to determine the mechanism and biologic importance of these changes.