Circulating levels of PRO-C3 reflect liver fibrosis and liver function in HIV positive patients receiving modern cART.
Leona DoldMette J NielsenMichael PraktiknjoCarolynne Schwarze-ZanderChristoph BoeseckeRobert SchierwagenRaphael MohrJan-Christian WasmuthChristian JansenJenny BischoffJürgen Kurt RockstrohMorten A KarsdalUlrich SpenglerJonel TrebickaDiana J LeemingPublished in: PloS one (2019)
The formation marker of type III collagen, PRO-C3 not only reflects liver fibrosis, but might also mirror liver dysfunction in HIV positive patients receiving cART. Therefore, the circulating levels of PRO-C3 might be suitable to monitor progression of liver fibrosis and deterioration of liver function in HIV positive patients receiving cART.