Neuroprotective effects of dexpanthenol on streptozotocin-induced neuronal damage in rats.

Mümin Alper ErdoganGurkan YigitturkOytun ErbasDilek Taskıran

Published in: Drug and chemical toxicology (2021)

Dexpanthenol significantly prevented the memory deficit induced by ICV-STZ through mitigating neuronal loss in hippocampus, cholinergic deficiency and neuroinflammation in rats. These findings suggest that dexpanthenol may be beneficial for treating memory impairment.

Keyphrases

diabetic rats
oxidative stress
cerebral ischemia
working memory
subarachnoid hemorrhage
traumatic brain injury
cognitive impairment
blood brain barrier
high fat diet
high glucose
lipopolysaccharide induced
drug induced
adipose tissue
skeletal muscle